Publications

Too big not to fail: emerging evidence for size-induced senescence
Manohar S and Neurohr GE 
The FEBS Journal, 2024, vol. 291, no 11, p. 2291-2305
DOI:external page 10.1111/febs.16983     Research collection     PMID: 37986656

Genome homeostasis defects drive enlarged cells into senescence
Manohar S, Estrada ME, Uliana F, Vuina K, Alvarez PM, de Bruin RAM, and Neurohr GE
Molecular Cell, 2023, vol. 83, no 22, p. 4032-4046. e6
DOI: external page 10.1016/j.molcel.2023.10.018     Research collection     PMID: 37977116   

The environmental stress response regulates ribosome content in cell cycle-arrested S. cerevisiae
Terhorst A, Sandikci A, Whittaker CA, Szórádi T, Holt LJ, Neurohr GE, and Amon A
Frontiers in Cell and Developmental Biology, 2023, vol. 11, p. 1118766
DOI: external page 10.3389/fcell.2023.1118766     Research collection     PMID: 37123399

Hybrid machine-learning framework for volumetric segmentation and quantification of vacuoles in individual yeast cells using holotomography
Lee M, Kunzi M, Neurohr GE, Lee SS, and Park Y
Biomedical Optics Express, 2023, vol. 14, no 9, p. 4567-4578
DOI: external page 10.1364/BOE.498475     Research collection     PMID: 37791265

Cell cycle progression defects and impaired DNA damage signaling drive enlarged cells into senescence
Manohar S, Estrada ME, Uliana F, and Neurohr GE
BioRxiv, 2022, p. 2022.09. 08.506740
external page DOI: 10.1101/2022.09.08.506740    

Relevance and Regulation of Cell Density
Neurohr GE, and Amon A
Trends in cell biology, 2020, vol. 30, no 3, p. 213-225
DOI: external page 10.1016/j.tcb.2019.12.006     PMID: 31980346

Excessive cell growth causes cytoplasm dilution and contributes to senescence
Neurohr GE, Terry RL, Lengefeld J, Bonney M, Brittingham GP, Moretto F, Miettinen TP, Pontano Vaites L, Soares LM, Paulo J, Harper W, Buratowski S, Manalis S, van Werven FJ, Holt LJ and Amon A
Cell, 2019, vol. 176, no 5, p. 1083-1097. e18
DOI: external page 10.1016/j.cell.2019.01.018     PMID: 30739799

Deregulation of the G1/S-phase transition is the proximal cause of mortality in old yeast mother cells
Neurohr GE, Terry RL, Sandikci A, Zou K, Li H, and Amon A
Genes & development, 2018, vol. 32, no 15-16, p. 1075-1084
DOI: external page 10.1101/gad.312140.118     PMID: 30042134

A midzone-based ruler adjusts chromosome compaction to anaphase spindle length
Neurohr GE, Naegeli A, Titos I, Theler D, Greber B, Díez J, Gabaldón T, Mendoza M, and Barral Y
Science, 2011, vol. 332, no 6028, p. 465-468
DOI: external page 10.1126/science.1201578     PMID: 21393511

The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress
Amaral N, Vendrell A, Funaya C, Idrissi FZ, Maier M, Kumar A, Neurohr GE, Colomina N, Torres-Rosell J, Geli MI, and Mendoza M
Nature cell biology, 2016, vol. 18, no 5, p. 516-526
DOI: external page 10.1038/ncb3343     PMID: 27111841

Cdc14 Localization as a Marker for Mitotic Exit: In Vivo Quantitative Analysis of Cdc14 Release
Neurohr GE and Mendoza M
The Mitotic Exit Network: Methods and Protocols, 2017, p. 59-67
DOI: external page 10.1007/978-1-4939-6502-1_5     PMID: 27826856

Assays for mitotic chromosome condensation in live yeast and mammalian cells
Neurohr GE and Gerlich DW
Chromosome research, 2009, vol. 17, p. 145-154
DOI: external page 10.1007/s10577-008-9010-1     PMID: 19308697